AI tools & workflows
AI‑Designed IRES: Myth‑Busting Cap‑Dependent Promoters and the Next Wave of Gene‑Therapy Vectors
Imagine a gene-therapy vector that packs more payload, sidesteps innate immunity, and delivers a three-fold boost in therapeutic protein - all without a traditional promoter. That scenario is no longer a distant fantasy. In 2024, the convergence of transformer models and ribosome-profiling data has produced synthetic IRES elements that rewrite